The high-throughput screening and quantitation of compounds is a crucial process performed in routine analyses across forensic, environmental and food safety laboratories. The new Thermo Scientific TraceFinder 5.1 software helps scientists simplify and optimise quantitation with improved integration of difficult peaks, delivering consistent results between users. The software features the ability to search both a Thermo Fisher library and a custom library in the same method, providing access to an increased number of compounds. Laboratory scientists and technicians also benefit from streamlined reporting, with easily customisable reports that avoid complex formatting and formulae.