The CONFIRM Sequence app on the waters_connect software platform helps scientists using a Waters LC-MS System to confirm the nucleic acid sequence of therapeutics and identify impurities that could compromise product safety and efficacy. The CONFIRM Sequence app eliminates 50 % of the time it takes for post-processing data review, accelerating characterisation and development of nucleic acid therapeutics. The new CONFIRM Sequence app is the first sequencing tool to integrate compliance-ready data acquisition, processing and reporting, making it suitable for deployment in regulated development and Good Manufacturing Practice (GMP) labs.