New workflow for phenomics research and validation

Bruker have introduced a new workflow for phenomics research and validation, where MS is complementary to NMR, using flow injection analysis-magnetic resonance mass spectrometry (FIA-MRMS). FIA-MRMS can generate molecular formulae for >1000 medium level metabolites, and reveals new metabolites not seen in LC-MS, e.g. polar compounds. With MetaboScape™ software, high confidence metabolite annotation is based on MRMS extreme mass resolution >1 million and mass accuracy ~0.2 ppm. High throughput, LC-free FIA measures >200 samples/day, enabling large cohorts and longitudinal studies in phenomics.