Material dissolved in the liquid at the port tip is immediately transported into the mass spectrometer, ionised, detected and characterised.
Thanks to seven years of work done at the RIKEN Quantitative Biology Center and Hiroshima University, scientists can take a peek into a single plant cell and—within minutes—get a view of the small molecules, including metabolites, hormones, nutrients and lipids inside it by mass spectrometry.
Agilent is collaborating with researchers from Weill Cornell Medical College, in New York, USA, to investigate the molecular underpinnings of sporadic amyotrophic lateral sclerosis using a multi-omics approach.
Watch the imprint of a tyre track in soft mud, and it will slowly blur, the ridges of the pattern gradually flowing into the valleys. Using imaging mass spectrometry, researchers at the National Institute of Standards and Technology (NIST) have tested the theory that a similar effect could be used to give forensic scientists something they have long wished for: a way to date fingerprints.
SCIEX has announced that Aarhus University Hospital in Denmark has invested in SCIEX QTRAP® 6500 technology to develop novel mass spectrometry-based assays for clinical research laboratories. Scientists at the hospital’s Department of Clinical Biochemistry are using the QTRAP 6500 LC-MS/MS system for advanced clinical research.
Canadian researchers have used SERS to screen blood samples for molecular traces that indicate the presence of precancerous polyps in the colon, a key warning sign for colon cancer. Their results may yield a cheaper and less invasive initial screening test for colon cancer that could complement colonoscopy, though further clinical trials will need to demonstrate the safety and effectiveness of the blood test before it is routinely used.
The combination of ab initio numerical experiments and theory shows that optical tunnelling of an electron from an atom can occur instantaneously.
A major advance in solution-phase soft X-ray spectroscopy has been achieved utilising a new liquid flatjet system, paving the way for novel steady-state and time-resolved experiments.
Raman microscopy is being used alongside high-resolution X-ray diffraction to unpick the reasons for crystallographic defects in SiC bulk crystal and epitaxial film, which limit the commercialisation of SiC devices.
A partnership between the Institut de recherches cliniques de Montréal and Nuclea Biotechnologies has been formed to use quantitative mass spectrometry-based assays for insulin, proinsulin and c-peptide to determine risk and progression of type 2 diabetes.
In initial tests, a novel near infrared spectroscopy device assesses shock severity as accurately as a standard blood sample, without a single needle prick.
Researchers at the University of Birmingham, UK, have published results that suggest a non-invasive breath test for liver disease using a proton transfer reaction mass spectrometer.
Renishaw’s Spectroscopy Products Division (SPD) has moved to the new Renishaw Innovation Centre located at the company’s New Mills headquarters in Wotton-under-Edge, Gloucestershire, UK. This is a brand new building providing an additional 153,000 ft2 of space for Renishaw adjacent to the company’s iconic HQ, which is a converted 19th century woollen mill. The RIC was opened on 7 July 2015 by HRH The Princess Royal.
Combining fluorescence spectroscopy and “stochastic optical reconstruction microscopy” enables the imaging of single molecules with unprecedented spectral and spatial resolution, thus leading to the first “true-colour” super-resolution microscope.
Ocean Optics has increased support for its EMEA (Europe, Middle East, Africa) business with the appointment of Zimon Norlin to the position of EMEA Service and Operations Manager. Norlin will be charged with growing regional access to Ocean Optics’ spectroscopy products and applications knowledge.
Unique “graffiti” on the walls of a cave in central China describes the effects drought had on the local population over the past 500 years. Stable isotope and elemental analysis of stalactites have been able to confirm the climate variations.
VTT Technical Research Centre of Finland has developed a miniature gas sensor that can be connected to mobile devices. Gas measurements made with smartphones will make activities such as the detection of internal air problems easier. In addition, sleep quality will be measurable with greater precision, using mobile healthcare applications which gauge carbon dioxide quantities.
Researchers have solved a key obstacle in creating the underlying technology for miniature optical sensors to detect chemicals and biological compounds, high-precision spectroscopy, ultra-stable microwave sources, and optical communications systems that transmit greater volumes of information with better quality.
Raman spectroscopy helps lithium-air batteries live up to their promise: we could one day be driving electric cars 500 miles or more without recharging, or using laptops for weeks without having to plug in. They could also replace lithium-ion batteries, currently the standard in many consumer electronics.
An international collaboration including scientists from the Florida campus of The Scripps Research Institute (TSRI) has used hydrogen–deuterium exchange mass spectrometry to determine the structure of a plant hormone that plays a crucial role in regulating plants’ responses to insects and disease-causing microorganisms as well as normal growth and development.